Description

Gdp CAS NO 146-91-8 is a high-purity chemical compound, also known as Guanosine 5'-diphosphate, which serves as a critical nucleotide derivative in biochemical research and pharmaceutical development. Its primary value lies in its role as a key substrate and intermediate in enzymatic studies, metabolic pathway analysis, and the synthesis of more complex biomolecules. This product is essential for research institutions, biotechnology companies, and pharmaceutical manufacturers engaged in nucleotide metabolism, signal transduction research, and the development of diagnostic kits or therapeutic agents.

Application

• Biochemical Research: Used as a fundamental substrate for studying enzyme kinetics, particularly for kinases, synthetases, and other GTP/GDP-binding proteins.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of nucleotide-based prodrugs and antiviral compounds.
• Diagnostic Reagent Manufacturing: Employed in the formulation of assay kits for monitoring cellular energy status (ATP/ADP/GTP/GDP ratios) and metabolic disorders.
• Cell Signaling Studies: Essential for investigating G-protein coupled receptor (GPCR) pathways and intracellular signal transduction mechanisms.
• Metabolic Pathway Analysis: Utilized in in vitro reconstitution studies of the Krebs cycle, gluconeogenesis, and other nucleotide-dependent metabolic processes.
• Enzyme Cofactor: Acts as a cofactor or allosteric modulator for various enzymes in purine and pyrimidine biosynthesis pathways.

Basic Information

Item	Detail
Product Name	Gdp CAS NO 146-91-8
CAS No.	146-91-8
Molecular Formula	C10H15N5O11P2
Molecular Weight	443.20 g/mol
Synonyms	Guanosine 5'-diphosphate; GDP; Guanosine diphosphate; 5'-GDP; Guanosine 5'-pyrophosphate; EINECS 205-687-8; Guanosinediphosphoric acid
EINECS	205-687-8

Quality Control

Our Gdp CAS NO 146-91-8 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize condensation and moisture uptake. For extended storage under inert atmosphere, please contact our technical team.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	2.5 - 4.5
Endotoxin (LAL)	< 10 EU/mg (for applicable grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.