Description

3-Iodo-4-Methoxybenzonitrile is a versatile halogenated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an electron-withdrawing cyano group and an electron-donating methoxy group adjacent to the iodine substituent, makes it a valuable precursor for constructing complex molecules. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis, enabling new cross-coupling and functionalization reactions.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers, due to its functionalized aromatic core.
• Chemical Biology Probe Synthesis: Useful for creating tagged molecules or affinity probes for studying biological processes and target identification.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring specific halogenated intermediates.

Basic Information

Product Name	3-Iodo-4-Methoxybenzonitrile
CAS No.	82504-06-1
Molecular Formula	C8H6INO
Molecular Weight	259.05 g/mol
Synonyms	4-Methoxy-3-iodobenzonitrile; 3-Iodo-4-methoxybenzonitrile; 3-Iodo-p-anisonitrile; 4-Cyano-2-iodoanisole; Benzonitrile, 3-iodo-4-methoxy-; 2-Iodo-4-cyanoanisole
EINECS	Contact for details

Quality Control

Our 3-Iodo-4-Methoxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.