Description

S-Nitroso-Coenzyme A is a chemically modified, nitrosylated derivative of the essential metabolic cofactor Coenzyme A. This compound is of significant interest as a biochemical research tool and a precursor for studying S-nitrosylation, a critical post-translational modification involved in cellular signaling and redox regulation. It is primarily utilized by researchers and developers in the fields of biochemistry, enzymology, and pharmaceutical R&D for investigating nitric oxide-mediated pathways and protein function.

Application

• Biochemical Research: A key reagent for studying S-nitrosylation mechanisms and nitric oxide (NO) signaling pathways in vitro.
• Enzyme Activity Studies: Used to investigate the modulation of enzyme function through targeted S-nitrosylation of active-site cysteine residues.
• Pharmaceutical Development: Serves as a tool compound in drug discovery programs targeting redox-based diseases and NO-related disorders.
• Metabolic Pathway Analysis: Employed to probe the impact of nitrosative stress on central metabolic pathways involving Coenzyme A.
• Proteomics Research: Used as a substrate or labeling agent in studies aimed at identifying and characterizing S-nitrosylated proteins.
• Academic Research: Fundamental research tool in university and institutional labs for cell signaling and post-translational modification studies.

Basic Information

Product Name	S-Nitroso-Coenzyme A
CAS No.	82494-50-6
Molecular Formula	C21H35N8O17P3S
Molecular Weight	828.52 g/mol
Synonyms	S-Nitroso-CoA; Nitroso Coenzyme A; CoA-SNO; S-Nitroso-Coenzyme A disodium salt; S-Nitrosothiol CoA; 3'-dephospho-S-nitroso-CoA; S-Nitroso-Coenzyme A trisodium salt
EINECS	Contact for details

Quality Control

Our S-Nitroso-Coenzyme A is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and degradation. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.