Description

3-[2-[3-[(2,4-Dihydroxy-3,3-Dimethyl-Butanoyl)Amino]Propanoylamino]Ethylsulfanyl]-7-Oxo-6-(1-Sulfooxyethyl)-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid is a chemically synthesized intermediate of significant importance in advanced pharmaceutical manufacturing. This compound serves as a critical building block in the synthesis of novel β-lactam antibiotics and other complex therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract synthesis organizations engaged in developing next-generation anti-infective drugs.

Application

• Key Intermediate for β-Lactam Antibiotics: Serves as a crucial precursor in the synthesis of advanced cephalosporin and carbapenem class antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and development of new antibacterial compounds with modified side chains for enhanced efficacy.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex, functionalized azabicyclic ring systems.
• Active Pharmaceutical Ingredient (API) Manufacturing: Integrated into the production process of specific, proprietary antibiotic APIs.
• Bioconjugation Studies: Potential use in creating antibiotic-drug conjugates for targeted delivery, leveraging its functional groups.

Basic Information

Product Name	3-[2-[3-[(2,4-Dihydroxy-3,3-Dimethyl-Butanoyl)Amino]Propanoylamino]Ethylsulfanyl]-7-Oxo-6-(1-Sulfooxyethyl)-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid
CAS No.	82475-09-0
Molecular Formula	C20H31N3O11S2
Molecular Weight	553.60 g/mol
Synonyms	(6R,7R)-7-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid derivative; Cephalosporin C-7 side chain intermediate; 7-ACA derivative with sulfooxyethyl group; 3-(2-{3-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]propanamido}ethylsulfanyl)-7-oxo-6-(1-sulfooxyethyl)-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; Advanced cephalosporin nucleus; β-lactam intermediate 82475-09-0.
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to strict cGMP (current Good Manufacturing Practice) guidelines to ensure batch-to-batch consistency and traceability. Quality is verified through a comprehensive suite of analytical techniques including HPLC for purity and chiral integrity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.