Description

Boc-D-3-Trifluoromethylphe CAS NO 82317-82-6 is a high-purity, protected amino acid derivative featuring a trifluoromethyl group on the phenylalanine side chain. This compound is a critical chiral building block in modern pharmaceutical research and development, offering enhanced metabolic stability and lipophilicity to peptide-based drug candidates. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic peptides and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the solid-phase and solution-phase synthesis of bioactive peptides.
• Protease Inhibitor Development: Incorporation into peptide sequences to create potent inhibitors targeting specific enzymes.
• PET Tracer Precursor: Serves as a precursor in the synthesis of positron emission tomography (PET) imaging agents, leveraging the fluorine-18 isotope.
• Chemical Biology Research: Used in the study of protein-protein interactions and enzyme mechanisms by introducing a stable, fluorine-labeled probe.
• Agrochemical Research: Employed in the discovery of novel peptide-based pesticides and fungicides.
• Academic Research: A valuable reagent for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	Boc-D-3-Trifluoromethylphe CAS NO 82317-82-6
CAS No.	82317-82-6
Molecular Formula	C15H18F3NO4
Molecular Weight	333.31 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-3-(trifluoromethyl)-D-phenylalanine; Boc-3-CF3-D-Phe-OH; (2R)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[3-(trifluoromethyl)phenyl]propanoic acid; N-Boc-3-Trifluoromethyl-D-phenylalanine; tert-Butyl (R)-2-amino-3-(3-(trifluoromethyl)phenyl)propanoate; Boc-D-Phe(3-CF3)-OH; Boc-D-β-(3-Trifluoromethylphenyl)alanine
EINECS	Contact for details

Quality Control

Our Boc-D-3-Trifluoromethylphe is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards for fine chemical production, and specifications can be tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under standard laboratory conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.