Description

H-Lys(Cyc)-Oh CAS NO 82277-17-6 is a specialized, high-purity amino acid derivative featuring a cyclized side chain modification. This compound is critical for advanced peptide synthesis and pharmaceutical research, offering precise structural control for developing novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on peptide-based drug discovery and biochemical applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the solid-phase and solution-phase synthesis of complex therapeutic peptides.
• Drug Discovery Research: Used in structure-activity relationship (SAR) studies to investigate the impact of side-chain cyclization on peptide stability and bioactivity.
• Bioconjugation: Acts as a specialized linker or spacer molecule for creating peptide-drug conjugates or labeled probes.
• Biochemical Tool: Employed in the development of enzyme inhibitors, receptor ligands, and other bioactive peptide analogs for research purposes.
• Cosmeceutical Peptides: Incorporated into the design of stabilized peptide sequences for advanced skincare and cosmetic formulations.

Basic Information

Product Name	H-Lys(Cyc)-Oh
CAS No.	82277-17-6
Molecular Formula	C9H16N2O3
Molecular Weight	200.24 g/mol
Synonyms	N6-(Tetrahydro-2H-pyran-2-yl)-L-lysine; L-Lysine, N6-(tetrahydro-2H-pyran-2-yl)-; Lys(Thp)-OH; Fmoc-Lys(Thp)-OH (precursor); H-Lys(Thp)-OH; N-ε-THP-L-lysine; (2S)-2-Amino-6-[(oxan-2-yl)amino]hexanoic acid; Nε-THP-L-lysine
EINECS	Contact for details

Quality Control

Our H-Lys(Cyc)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	[α]20/D: Specific range available on COA
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.