Description

Angiotensinogen (6-13) is a specific peptide fragment derived from the angiotensinogen protein, a key component of the renin-angiotensin system. This compound is of significant value as a high-purity biochemical tool for advanced research and diagnostic development. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of in vitro diagnostic (IVD) kits for studying hypertension, cardiovascular diseases, and related biochemical pathways.

Application

• Biochemical Research: Used as a reference standard or substrate in enzymatic studies of the renin-angiotensin-aldosterone system (RAAS).
• Pharmaceutical Development: Serves as a key intermediate or analytical standard in the research and development of antihypertensive drugs and cardiovascular therapies.
• Diagnostic Assays: Employed as a critical antigen or calibrator in the production of immunoassay kits for measuring renin activity or angiotensin-related peptides.
• Mechanistic Studies: Utilized in cell-based and in vitro assays to investigate the molecular mechanisms of blood pressure regulation and vascular function.
• Peptide Chemistry: Acts as a building block or model compound for synthetic peptide chemistry and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Angiotensinogen (6-13)
CAS No.	82252-46-8
Molecular Formula	C41H62N12O11
Molecular Weight	899.0 g/mol
Synonyms	Angiotensinogen Fragment 6-13; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe; DRVYIHPF; Human Angiotensinogen (6-13); Angiotensin I (1-8); [Des-Asp1, Des-Leu10]-Angiotensin I
EINECS	Contact for details

Quality Control

Our Angiotensinogen (6-13) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 70.0%
Solubility	Soluble in water, dimethyl sulfoxide (DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.