Description

Propargyl 4-Bromobenzamide is a specialized organic building block featuring both a bromoaryl and a propargyl amide functional group. This unique bifunctional structure makes it a valuable intermediate for advanced synthesis in pharmaceutical and agrochemical research, enabling the construction of complex molecular architectures. It is primarily sought by R&D chemists and process development scientists working on new active ingredients, particularly in medicinal chemistry for hit-to-lead optimization and the development of novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting kinase inhibition or requiring acetylene-based click chemistry for bioconjugation.
• Agrochemical Synthesis: Serves as a precursor in the design and synthesis of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of advanced polymers and functional materials, where the acetylene group can participate in polymerization or cross-linking reactions.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	Propargyl 4-Bromobenzamide
CAS No.	82225-32-9
Molecular Formula	C10H8BrNO
Molecular Weight	238.08 g/mol
Synonyms	4-Bromo-N-(prop-2-yn-1-yl)benzamide; N-Propargyl-4-bromobenzamide; 4-Bromobenzoic Acid Propargylamide; Propargyl-p-bromobenzamide; (4-Bromophenyl)-N-(2-propynyl)carboxamide; 82225-32-9; p-Bromo-N-propargylbenzamide
EINECS	Contact for details

Quality Control

Our Propargyl 4-Bromobenzamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.