Description

3-(Trifluoromethylthio)Phenylacetonitrile is a versatile fluorinated aromatic nitrile building block, distinguished by its trifluoromethylthio (-SCF₃) functional group. This compound is valued for its role in introducing the lipophilic and metabolically stable SCF₃ moiety into target molecules, a key strategy in modern agrochemical and pharmaceutical design. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced material science sectors for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas requiring enhanced membrane permeability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the SCF₃ group can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display and lighting technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitutions to create complex, fluorinated aromatic structures.
• Chemical Research & Development: Utilized in academic and industrial labs for exploring new reactions and properties of sulfur- and fluorine-containing compounds.

Basic Information

Item	Details
Product Name	3-(Trifluoromethylthio)Phenylacetonitrile
CAS No.	82174-09-2
Molecular Formula	C₉H₆F₃NS
Molecular Weight	217.21 g/mol
Synonyms	α-(3-((Trifluoromethyl)thio)phenyl)acetonitrile; (3-(Trifluoromethylthio)phenyl)acetonitrile; 2-[3-(Trifluoromethylsulfanyl)phenyl]acetonitrile; m-(Trifluoromethylthio)phenylacetonitrile; 3-(Trifluoromethylsulfanyl)benzeneacetonitrile; 3-SCF₃-Phenylacetonitrile; 82174-09-2; 3-Trifluoromethylthiobenzyl cyanide
EINECS	Contact for details

Quality Control

Our production of 3-(Trifluoromethylthio)Phenylacetonitrile adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and MS to confirm identity and quantify purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.