Description

1,25,26-Trihydroxy-23-Oxo-Vitamin D3 is a high-purity, synthetic vitamin D analog with significant biological activity. This compound is critical for advanced research into calcium metabolism, cell differentiation, and immune system regulation. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and manufacturers of high-value biochemical reagents for developing novel therapeutic agents and conducting precise mechanistic studies.

Application

• Pharmaceutical Research & Development: A key reference standard and active pharmaceutical ingredient (API) intermediate for investigating new treatments targeting osteoporosis, psoriasis, and certain cancers.
• Biochemical Research: Used as a potent ligand to study the Vitamin D receptor (VDR) signaling pathway, gene expression, and cellular differentiation processes in vitro.
• Metabolic Studies: Essential for probing the complex metabolism of vitamin D and the biological roles of its hydroxylated and oxo-derivatives.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for method development and quality control in HPLC, LC-MS, and other analytical techniques.

Basic Information

Product Name	1,25,26-Trihydroxy-23-Oxo-Vitamin D3
CAS No.	82095-24-7
Molecular Formula	C₂₇H₄₂O₆
Molecular Weight	462.62 g/mol
Synonyms	23-Oxo-1,25,26-trihydroxyvitamin D3; 23-Oxocalcitriol; 1,25,26-Trihydroxy-23-oxocholecalciferol; 23-Oxo-1α,25,26-trihydroxyvitamin D₃; 23-Oxocalcitriol analog; Vitamin D3 metabolite analog; 1α,25,26-Trihydroxy-23-oxovitamin D₃
EINECS	Contact for details

Quality Control

Our 1,25,26-Trihydroxy-23-Oxo-Vitamin D3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. For short-term use, store at 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.