Description

2,4,6-Trifluorobenzamide is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and specialty materials, where its trifluoromethyl-substituted benzamide structure imparts desirable metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated compounds used in electronic displays and organic light-emitting diodes.
• Polymer Modification: Incorporated into specialty polymers to alter thermal stability, chemical resistance, and surface properties.
• Cross-Coupling Reactions: Utilized in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex, fluorinated biaryl structures.
• Research & Development: A valuable reagent for academic and industrial research exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	2,4,6-Trifluorobenzamide
CAS No.	82019-50-9
Molecular Formula	C7H4F3NO
Molecular Weight	175.11 g/mol
Synonyms	2,4,6-Trifluorobenzoic acid amide; Benzamide, 2,4,6-trifluoro-; 2,4,6-Trifluorobenzenecarboxamide; 82019-50-9; AI3-52362; BRN 2203625; CTK8G8125; NSC 403079; ZINC000008714773; 2,4,6-Trifluorobenzoylamide
EINECS	Contact for details

Quality Control

Our 2,4,6-Trifluorobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.