Description

8-Oxyguanine is a significant oxidized derivative of guanine, playing a crucial role in the study of oxidative DNA damage and repair mechanisms. Its importance lies in its function as a biomarker for oxidative stress and its utility in advanced biochemical research. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors, particularly those focused on oncology, aging, and genetic toxicology.

Application

• Biochemical Research: A critical standard and reagent for studying oxidative DNA damage, repair pathways, and mutagenesis.
• Diagnostic Development: Used in the research and production of diagnostic kits and assays for measuring oxidative stress biomarkers in biological samples.
• Pharmaceutical R&D: Serves as a reference compound in drug discovery programs targeting diseases linked to oxidative stress, such as cancer and neurodegenerative disorders.
• Academic Research: Employed in universities and research institutes for fundamental studies in biochemistry, molecular biology, and free radical chemistry.
• Quality Control Standards: Acts as a certified reference material (CRM) for calibrating analytical instruments like HPLC and LC-MS in laboratories.

Basic Information

Product Name	8-Oxyguanine
CAS No.	82014-86-6
Molecular Formula	C5H5N5O2
Molecular Weight	167.13 g/mol
Synonyms	8-Hydroxyguanine; 8-Oxo-7,8-dihydroguanine; 8-OxoGua; 8-OH-Gua; 8-OxoG; 7,8-Dihydro-8-oxoguanine; Oxo8dG; Guan-8-ol
EINECS	Contact for details

Quality Control

Our 8-Oxyguanine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.