Description

Butanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-4,4-Difluoro- is a high-value, fluorinated amino acid derivative with a protected amine group, serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture, particularly for introducing difluoromethylene and protected amino functionalities into target molecules. It is primarily utilized in the development of pharmaceutical intermediates, agrochemicals, and specialized peptidomimetics.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of active pharmaceutical ingredients (APIs), especially those incorporating fluorinated amino acids to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and pesticides where the difluoro and tert-butoxycarbonyl (Boc) protected amine groups confer specific biological activity and selectivity.
• Peptidomimetic & Protease Inhibitor Development: Serves as a crucial building block for designing peptide analogs and enzyme inhibitors, leveraging the fluorine atoms to influence binding affinity and conformational properties.
• Organic Synthesis Reagent: Employed in medicinal and combinatorial chemistry for the construction of complex, fluorinated organic molecules and chemical libraries.
• Material Science Research: Potential applications in developing specialty polymers and advanced materials with unique properties derived from its fluorinated structure.

Basic Information

Item	Details
Product Name	Butanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-4,4-Difluoro-
CAS No.	81982-56-1
Molecular Formula	C9H15F2NO4
Molecular Weight	239.22 g/mol
Synonyms	4,4-Difluoro-3-[(tert-butoxycarbonyl)amino]butanoic acid; 3-[(Boc)amino]-4,4-difluorobutanoic acid; Boc-4,4-difluoro-DL-homoalanine; 4,4-Difluoro-3-[(tert-butoxycarbonyl)amino]butyric acid; (R,S)-3-[(tert-Butoxycarbonyl)amino]-4,4-difluorobutanoic acid; 3-Amino-4,4-difluorobutanoic acid Boc derivative; N-Boc-3-amino-4,4-difluorobutanoic acid
EINECS	Contact for details

Quality Control

Our production of Butanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-4,4-Difluoro- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the exacting standards required for GMP-grade intermediates and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.