Description

Mianserin-D3 CAS NO 81957-76-8 is a deuterated analog of the pharmaceutical compound Mianserin, serving as a high-purity internal standard for analytical chemistry. This stable isotope-labeled compound is critical for ensuring the accuracy and reliability of quantitative analyses, particularly in mass spectrometry. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, forensic, and clinical diagnostics sectors who require precise measurement of Mianserin and its metabolites.

Application

• Primary use as an internal standard for the quantification of Mianserin in biological matrices (e.g., plasma, serum, urine) via LC-MS/MS and GC-MS.
• Critical component in pharmaceutical research and development for pharmacokinetic and metabolism studies.
• Essential for forensic and clinical toxicology laboratories conducting drug monitoring and confirmation analyses.
• Used in the development and validation of regulatory-compliant analytical methods (e.g., for FDA, EMA submissions).
• Application in reference material production for calibrators and controls in diagnostic assays.
• Supporting academic research investigating the pharmacological profile and metabolic pathways of tetracyclic antidepressants.

Basic Information

Product Name	Mianserin-D3
CAS No.	81957-76-8
Molecular Formula	C18H17D3N2
Molecular Weight	267.38 g/mol
Synonyms	Mianserin-d3; Deuterated Mianserin; 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine-d3; 6-Azaphenothiazine-d3; Mianserin (methyl-d3); Org GB 94-d3; Tolvon-d3; Tetramethylpyrazine-d3 (context-specific)
EINECS	Contact for details

Quality Control

Every batch of Mianserin-D3 CAS NO 81957-76-8 is manufactured and analyzed under strict quality systems to ensure the high chemical purity and isotopic enrichment required for analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed data on purity, isotopic purity (D-enrichment), and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.