Description

1-Pyrenebutyryl-Coenzyme A is a specialized, high-purity biochemical reagent that serves as a critical tool in enzymatic and metabolic research. This compound is valued for its role as a substrate or inhibitor in studies involving acyl-CoA synthetases, dehydrogenases, and other enzymes central to lipid metabolism and cellular bioenergetics. It is essential for researchers and developers in the fields of biochemistry, pharmaceutical discovery, and diagnostic assay development who require precise and reliable coenzyme A derivatives.

Application

• Enzymology Research: Used as a substrate for studying the kinetics and mechanism of acyl-CoA utilizing enzymes such as acyl-CoA synthetases and dehydrogenases.
• Metabolic Pathway Analysis: Employed in in vitro assays to investigate fatty acid oxidation, lipid biosynthesis, and other metabolic processes.
• Pharmaceutical Screening: Serves as a key reagent in high-throughput screening (HTS) campaigns to identify potential inhibitors or modulators of metabolic enzyme targets.
• Diagnostic Development: Utilized in the development of clinical diagnostic kits for measuring specific enzyme activities related to metabolic disorders.
• Fluorescence-Based Studies: The pyrene moiety allows for its application in fluorescence spectroscopy and labeling studies due to its intrinsic fluorescent properties.
• Bioconjugation & Probe Synthesis: Acts as a starting material or intermediate for synthesizing fluorescent probes or affinity labels for protein tagging.

Basic Information

Product Name	1-Pyrenebutyryl-Coenzyme A
CAS No.	81923-89-9
Molecular Formula	C40H56N7O17P3S
Molecular Weight	1047.90 g/mol
Synonyms	Pyrenebutyryl-CoA; 1-Pyrenebutanoyl-Coenzyme A; Coenzyme A, S-(4-(1-pyrenyl)butanoate); 4-(1-Pyrenyl)butanoyl-CoA; 1-Pyrenebutyryl CoA; PBCoA; 1-Pyrenebutyryl-CoA; S-[4-(1-Pyrenyl)butanoyl]coenzyme A
EINECS	Contact for details

Quality Control

Our 1-Pyrenebutyryl-Coenzyme A is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our global clientele in academic, pharmaceutical, and diagnostic industries.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	Yellow to orange lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (UV/VIS)	Conforms to reference spectrum
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.