Description

S-(3-Oxobutyl)Coenzyme A is a key biochemical intermediate, specifically a thioester derivative of coenzyme A. This compound is essential for researchers studying metabolic pathways, particularly those involving ketone body utilization and fatty acid metabolism. It is primarily utilized by biochemists, pharmaceutical R&D teams, and diagnostic manufacturers for enzyme assays, metabolic studies, and the development of analytical standards.

Application

• Biochemical Research: Critical substrate for studying enzymes like acetoacetyl-CoA synthetase and other acyl-CoA metabolizing enzymes.
• Metabolic Pathway Analysis: Used in in vitro assays to investigate ketone body metabolism, lipid biosynthesis, and energy homeostasis.
• Pharmaceutical Development: Serves as a reference standard or intermediate in drug discovery programs targeting metabolic disorders such as diabetes or obesity.
• Diagnostic Reagent Manufacturing: Incorporated into enzymatic test kits for clinical diagnostics to measure specific metabolic markers.
• Enzyme Kinetics & Characterization: Employed to determine kinetic parameters (Km, Vmax) and inhibition constants for relevant metabolic enzymes.

Basic Information

Product Name	S-(3-Oxobutyl)Coenzyme A
CAS No.	81790-81-0
Molecular Formula	C₂₅H₄₂N₇O₁₇P₃S
Molecular Weight	837.62 g/mol
Synonyms	Acetoacetyl-CoA; 3-Oxobutanoyl-CoA; S-Acetoacetylcoenzyme A; 3-Oxobutanoyl-Coenzyme A; Acetoacetyl Coenzyme A; Coenzyme A, S-(3-oxobutyl)-; Butanoyl-CoA, 3-oxo-; AcAc-CoA
EINECS	Contact for details

Quality Control

Our S-(3-Oxobutyl)Coenzyme A is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous internal quality standards to guarantee product integrity and performance in your assays.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity	Functional in standard enzyme assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.