Description

Antiarrhythmic Peptide is a synthetic peptide analog of a naturally occurring protein fragment with significant pharmacological activity. This compound is a critical research tool and active pharmaceutical ingredient (API) for investigating and developing novel treatments for cardiac arrhythmias. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on cardiovascular therapeutics.

Application

• Pharmaceutical Research & Development: As a reference standard and active compound in preclinical studies for novel antiarrhythmic drugs.
• Cardiovascular Pharmacology: Investigation of mechanisms underlying cardiac ion channel function and arrhythmia pathogenesis.
• Biochemical Assay Development: Used as a key reagent in developing high-throughput screening assays for cardiac drug discovery.
• Academic Research: Fundamental studies in physiology and medicine to understand heart muscle cell (cardiomyocyte) electrophysiology.
• API Intermediate: Serves as a building block or precursor in the synthesis of more complex peptide-based therapeutic candidates.
• Quality Control: Employed as a certified reference material (CRM) for analytical method validation and quality assurance of related pharmaceutical products.

Basic Information

Product Name	Antiarrhythmic Peptide
CAS No.	81771-37-1
Molecular Formula	C34H56N12O10
Molecular Weight	768.89 g/mol
Synonyms	AAP; Antiarrhythmic Peptide (AAP10); H-Gly-Ala-Gly-Hyp-Pro-Tyr-CONH2; Cyclo(Gly-Ala-Gly-4-hydroxy-Pro-Tyr); AAP10 Peptide; Anti-Arrhythmic Peptide 10; ZP123; GAP-134; (3S,6S,9S,12S,18R)-3-(2-Amino-2-oxoethyl)-6-[(1R)-1-hydroxyethyl]-9-(4-hydroxybenzyl)-12-(2-methylpropyl)-1,4,7,10,13-pentaazacyclooctadecane-2,5,8,11,14-pentone
EINECS	Contact for details

Quality Control

Our Antiarrhythmic Peptide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and related substances. Certificates of Analysis (COA) are provided with each shipment, detailing compliance with in-house specifications developed for research and pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0% (on anhydrous basis)
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.