Description

n-(3-Fluoro-Phenyl)-2,2-Dimethyl-Propionamide is a specialized fluorinated organic compound with the CAS number 81740-17-2, serving as a valuable building block in advanced chemical synthesis. Its structure, featuring a fluoro-phenyl group and a pivalamide moiety, makes it a critical intermediate for developing active pharmaceutical ingredients (APIs) and high-performance agrochemicals. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce fluorine for enhanced bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides where the fluorine atom improves lipophilicity and target binding.
• Material Science Research: Serves as a monomer or modifier in the creation of specialty polymers and advanced materials with specific optical or electronic properties.
• Ligand and Catalyst Development: Utilized in organometallic chemistry for constructing complex ligands used in catalytic processes.
• Chemical Biology Probes: Acts as a precursor for fluorescent tags or molecular probes used in biochemical and diagnostic research.

Basic Information

Product Name	n-(3-Fluoro-Phenyl)-2,2-Dimethyl-Propionamide
CAS No.	81740-17-2
Molecular Formula	C11H14FNO
Molecular Weight	195.23 g/mol
Synonyms	3-Fluoro-N-pivaloylaniline; N-(3-Fluorophenyl)pivalamide; Pivalic acid (3-fluoroanilide); 2,2-Dimethyl-N-(3-fluorophenyl)propanamide; 3'-Fluoropivalanilide; N-Pivaloyl-3-fluoroaniline; α,α-Dimethyl-3-fluorophenylacetamide; 81740-17-2
EINECS	Contact for details

Quality Control

Our n-(3-Fluoro-Phenyl)-2,2-Dimethyl-Propionamide is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.