Description

5-Fluoro-N,N,3-Trimethyl-2-Benzofurancarboxamide is a high-purity, fluorinated benzofuran derivative of significant interest in advanced chemical synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used as a precursor for synthesizing novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Potential building block for advanced organic electronic materials and specialty polymers due to its benzofuran core.
• Chemical Synthesis: Serves as a versatile fluorinated intermediate for introducing the 5-fluoro-benzofuran moiety into more complex molecular architectures.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	5-Fluoro-N,N,3-Trimethyl-2-Benzofurancarboxamide
CAS No.	81718-71-0
Molecular Formula	C₁₂H₁₄FNO₂
Molecular Weight	223.25 g/mol
Synonyms	5-Fluoro-3-methyl-N,N-dimethyl-1-benzofuran-2-carboxamide; 5-Fluoro-3-methyl-N,N-dimethylbenzofuran-2-carboxamide; 2-Benzofurancarboxamide, 5-fluoro-N,N,3-trimethyl-; 5-Fluoro-N,N,3-trimethylbenzo[b]furan-2-carboxamide; 81718-71-0; 5-Fluoro-3-methyl-N,N-dimethyl-2-benzofurancarboxamide
EINECS	Contact for details

Quality Control

Our 5-Fluoro-N,N,3-Trimethyl-2-Benzofurancarboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.