Description

p-Bromoacetamido Benzyl-EDTA is a specialized bifunctional chelating agent that serves as a critical intermediate in the synthesis of advanced diagnostic and therapeutic agents. Its core value lies in its ability to covalently bind to biomolecules via its reactive bromoacetamido group while simultaneously chelating metal ions with its EDTA moiety. This product is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing targeted radiopharmaceuticals, MRI contrast agents, and other metal-labeled probes for molecular imaging and therapy.

Application

• Radiopharmaceutical Precursor: Key intermediate for synthesizing chelator-antibody or chelator-peptide conjugates labeled with diagnostic (e.g., 99mTc, 68Ga) or therapeutic (e.g., 177Lu, 90Y) radioisotopes.
• MRI Contrast Agent Development: Used to create targeted contrast agents by conjugating the chelator to targeting vectors (antibodies, peptides) for complexing gadolinium (Gd3+) or other paramagnetic ions.
• Molecular Imaging Probes: Facilitates the development of dual-modality or multimodal imaging probes for techniques like SPECT/CT or PET/MRI.
• Protein & Antibody Labeling: Enables site-specific modification of proteins, antibodies, and other biomolecules with metal chelates for various in vitro and in vivo applications.
• Research Chemical: Serves as a valuable tool compound in academic and industrial research for studying metal-protein interactions, developing new chelation strategies, and exploring novel therapeutic platforms.
• Therapeutic Agent Conjugation: Potential use in creating drug conjugates where a cytotoxic payload is linked via a metal-chelate system for targeted delivery.

Basic Information

Product Name	p-Bromoacetamido Benzyl-EDTA
CAS No.	81677-64-7
Molecular Formula	C19H24BrN3O8
Molecular Weight	502.32 g/mol
Synonyms	4-Bromoacetamidobenzyl-EDTA; N-[p-[(Carboxymethyl)aminomethyl]phenyl]-N-[2-[bis(carboxymethyl)amino]ethyl]glycine, 4'-(bromoacetamide) derivative; (p-Bromoacetamidobenzyl)ethylenediaminetriacetic acid; BrAc-Bz-EDTA; Bz-EDTA-BrAc; Benzyl-EDTA-Bromoacetamide; Bifunctional Chelator BrAc-Bz-EDTA; 1-[4-[(2-Bromoacetyl)amino]phenyl]-N,N-bis(2-{[carboxylatomethyl](carboxymethyl)amino}ethyl)methanaminium
EINECS	Contact for details

Quality Control

Our p-Bromoacetamido Benzyl-EDTA is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for purity (HPLC), identity (NMR, IR), and specific tests for residual solvents and heavy metals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.