Description

Human m-Csf CAS NO 81627-83-0 is a highly purified recombinant protein, specifically the macrophage colony-stimulating factor, which plays a critical role in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. This product is essential for advanced life science research and biopharmaceutical development, offering a reliable tool for studying hematopoiesis, immunology, and cancer biology. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and academic sectors for cell culture applications, assay development, and therapeutic protein research.

Application

• Cell Culture & Differentiation: Used to support the in vitro growth, survival, and differentiation of monocytes and macrophages from bone marrow or peripheral blood progenitor cells.
• Immunology Research: A key reagent for studying macrophage function, innate immune responses, and the role of the mononuclear phagocyte system in health and disease.
• Hematopoiesis Studies: Essential for investigating the regulation of myeloid lineage development and bone marrow microenvironment interactions.
• Cancer Research: Employed in models studying tumor-associated macrophages (TAMs), their role in tumor progression, and potential immunotherapeutic targets.
• Biopharmaceutical Development: Serves as a critical growth factor component in the production and expansion of specific cell types for cell-based therapies and vaccine development.
• Assay Standard & Validation: Used as a reference standard in bioassays (e.g., cell proliferation assays) to quantify biological activity and ensure assay reproducibility.

Basic Information

Item	Detail
Product Name	Human m-Csf
CAS No.	81627-83-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Macrophage Colony-Stimulating Factor; M-CSF; CSF-1; Colony Stimulating Factor 1; Lanimostim; Recombinant Human M-CSF; rhM-CSF; Macrophage Growth Factor; MGI-IM
EINECS	Contact for details

Quality Control

Our Human m-Csf is produced under stringent conditions to ensure the highest levels of purity and biological activity. Each lot undergoes rigorous analytical testing, including identity confirmation, purity assessment by HPLC, endotoxin testing, and functional bioassay to verify specific activity. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (SDS-PAGE)	> 95%
Purity (HPLC)	> 98.0%
Endotoxin	< 1.0 EU/µg
Biological Activity	Determined by cell proliferation assay
Moisture Content (KF)	< 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.