Description

1-[3-[3,5-Bis(Trifluoromethyl)Phenyl]-2-Propynyl]-4-(tert-Butyl)Piperidinium Chloride is a high-purity, advanced pharmaceutical intermediate and organic building block. This compound is valued for its unique structural features, including the trifluoromethyl groups and piperidinium core, which impart significant chemical and metabolic stability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, particularly those targeting neurological and metabolic pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the stability of the trifluoromethyl groups.
• Ligand & Catalyst Precursor: Serves as a precursor for specialized ligands and phase-transfer catalysts in asymmetric synthesis.
• Material Science: Investigated for incorporation into specialty polymers and advanced organic materials requiring fluorine-containing moieties.
• Chemical Biology Probe: Utilized in the design of molecular probes for studying enzyme function and receptor interactions.

Basic Information

Product Name	1-[3-[3,5-Bis(Trifluoromethyl)Phenyl]-2-Propynyl]-4-(tert-Butyl)Piperidinium Chloride
CAS No.	81613-60-7
Molecular Formula	C21H24ClF6N
Molecular Weight	439.87 g/mol
Synonyms	4-tert-Butyl-1-[3-[3,5-bis(trifluoromethyl)phenyl]prop-2-yn-1-yl]piperidin-1-ium chloride; 1-[3-[3,5-Bis(trifluoromethyl)phenyl]prop-2-yn-1-yl]-4-tert-butylpiperidinium chloride; 4-(tert-Butyl)-1-[3-[3,5-bis(trifluoromethyl)phenyl]-2-propynyl]piperidinium chloride; N-[(3,5-Bis(trifluoromethyl)phenyl)ethynyl]-4-tert-butylpiperidinium chloride
EINECS	Contact for details

Quality Control

Our production of 1-[3-[3,5-Bis(Trifluoromethyl)Phenyl]-2-Propynyl]-4-(tert-Butyl)Piperidinium Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.