Description

Neuromedin C is a bioactive decapeptide belonging to the bombesin-like peptide family, identified by CAS NO 81608-30-2. This compound is a potent and selective agonist for the gastrin-releasing peptide receptor (GRPR), playing a critical role in cellular signaling pathways. It is an essential research-grade biochemical for scientists in pharmacology, neurobiology, and oncology. Its high purity and stability make it a valuable tool for in vitro and in vivo studies investigating receptor function, tumor biology, and neuroendocrine regulation.

Application

• Biomedical Research: Fundamental studies on bombesin receptor subtypes (BB1, BB2, BB3), their signaling cascades, and physiological roles.
• Cancer Research: Investigation of GRPR expression and function in various cancers, including prostate, breast, and lung cancers, for potential therapeutic targeting.
• Neurobiological Studies: Exploration of neuromedin C's role in the central and peripheral nervous systems, including its effects on smooth muscle contraction, feeding behavior, and thermoregulation.
• Drug Discovery & Development: Serving as a reference standard and pharmacological tool in high-throughput screening (HTS) assays to identify novel GRPR antagonists or agonists.
• In Vitro Diagnostics (IVD) Development: Used in the development and calibration of immunoassays (e.g., ELISA, RIA) for detecting bombesin-related peptides.
• Academic & Pharmaceutical R&D: A key reagent for universities, research institutes, and biopharmaceutical companies engaged in peptide hormone research and metabolic disorder studies.

Basic Information

Product Name	Neuromedin C
CAS No.	81608-30-2
Molecular Formula	C57H83N17O13S
Molecular Weight	1214.43 g/mol
Synonyms	Gastrin-Releasing Peptide (18-27); GRP (18-27); pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2; Litorin; Neuromedin C (human, rat, porcine); Ranatensin C; Bombesin-related peptide; BN/GRP
EINECS	Contact for details

Quality Control

Our Neuromedin C is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry (MS) for identity confirmation. We provide full traceability and Certificates of Analysis (COA) detailing purity, peptide content, water content, and residual solvent levels, available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and hydrolysis. Aliquot into single-use vials after reconstitution to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%
Biological Activity	Assayed by receptor binding or functional assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.