Description

2-(1H-1,2,4-Triazol-1-Yl)Acetonitrile is a versatile and high-value organic intermediate featuring a reactive nitrile group attached to a 1,2,4-triazole heterocycle. This unique structure makes it a critical building block for the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector. The compound's reactivity profile enables its use in creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of antifungal, antiviral, and other bioactive compounds containing the 1,2,4-triazole pharmacophore.
• Agrochemical Synthesis: Building block for developing new generations of fungicides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Used to create specialized nitrogen-containing ligands for coordination chemistry and catalytic applications.
• Material Science Research: Intermediate in the production of polymers, dyes, and other functional organic materials requiring heterocyclic components.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis projects.

Basic Information

Product Name	2-(1H-1,2,4-Triazol-1-Yl)Acetonitrile
CAS No.	81606-79-3
Molecular Formula	C4H4N4
Molecular Weight	108.10 g/mol
Synonyms	1H-1,2,4-Triazole-1-acetonitrile; (1H-1,2,4-Triazol-1-yl)acetonitrile; 1-Cyanomethyl-1H-1,2,4-triazole; 1-(Cyanomethyl)-1H-1,2,4-triazole; 2-(1,2,4-Triazol-1-yl)acetonitrile; Acetonitrile, 2-(1H-1,2,4-triazol-1-yl)-; 1H-1,2,4-Triazol-1-ylacetonitrile
EINECS	Contact for details

Quality Control

Our 2-(1H-1,2,4-Triazol-1-Yl)Acetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data with each shipment, including HPLC chromatograms for purity and identity confirmation. Certificates of Analysis (COA) detailing specific lot specifications are available upon request and are integral to our commitment to supply chain transparency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.