Description

Dansylpropranolol is a fluorescently labeled derivative of the β-blocker propranolol, incorporating a dansyl fluorophore. This compound is primarily valued as a critical research and diagnostic tool in biochemical and pharmacological studies. It is essential for scientists and professionals in pharmaceutical R&D, analytical chemistry, and life sciences who require high-purity chemical probes for receptor binding assays, fluorescence microscopy, and advanced analytical techniques.

Application

• Biochemical Research: Used as a fluorescent probe in receptor binding and enzyme inhibition studies.
• Pharmacological Assays: Serves as a tracer in competitive binding assays to study β-adrenergic receptors.
• Analytical Chemistry: Acts as a reference standard or derivatization agent in HPLC and LC-MS methods for propranolol analysis.
• Fluorescence Microscopy: Employed in cellular imaging to visualize drug localization and uptake.
• Drug Metabolism Studies: Utilized to investigate metabolic pathways and protein interactions of propranolol.
• Diagnostic Kit Development: A key component in the development of fluorescence-based diagnostic assays and kits.

Basic Information

Product Name	Dansylpropranolol
CAS No.	81591-69-7
Molecular Formula	C24H30N2O3S
Molecular Weight	426.58 g/mol
Synonyms	1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol Dansylamide; N-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-1-naphthalenedansylamide; Dansyl-Propranolol; Propranolol Dansyl Derivative; DNS-Propranolol; 5-(Dimethylamino)naphthalene-1-sulfonamide propranolol derivative
EINECS	Contact for details

Quality Control

Our Dansylpropranolol is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.