Description

Ethyl 2-(Trifluoromethyl)Phenylacetate is a high-purity fluorinated aromatic ester, serving as a critical building block in advanced chemical synthesis. Its value lies in the unique reactivity and stability imparted by the trifluoromethylphenyl moiety, enabling the development of sophisticated target molecules. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group to improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved performance and stability.
• Organic Synthesis & Catalysis: Employed as a versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis.
• Flavor & Fragrance Chemistry: Used in the synthesis of complex aromatic esters for high-value fragrance and flavor compounds.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorinated aromatic groups into polymers, enhancing material properties like chemical resistance and thermal stability.

Basic Information

Product Name	Ethyl 2-(Trifluoromethyl)Phenylacetate
CAS No.	81580-50-9
Molecular Formula	C11H11F3O2
Molecular Weight	232.20 g/mol
Synonyms	Ethyl (2-(Trifluoromethyl)phenyl)acetate; 2-(Trifluoromethyl)phenylacetic Acid Ethyl Ester; Ethyl α,α,α-Trifluoro-o-toluate; Ethyl 2-(Trifluoromethyl)benzeneacetate; o-Trifluoromethylphenylacetic Acid Ethyl Ester; NSC 405124; Ethyl (o-Trifluoromethylphenyl)acetate; Benzeneacetic acid, 2-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Trifluoromethyl)Phenylacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to minimize moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.460 - 1.470
Density (20°C)	1.20 - 1.30 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.