Description

Ajmaline Phenylbarbiturate is a specialized pharmaceutical intermediate and reference standard derived from the combination of the antiarrhythmic alkaloid ajmaline and phenylbarbiturate. This compound is critical for research and development in the pharmaceutical industry, particularly in the study of cardiac electrophysiology and the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in advanced medicinal chemistry and pharmacology.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug molecules targeting cardiac conditions.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories to ensure product purity and consistency.
• Biochemical Research: Employed in preclinical studies to investigate ion channel modulation and cardiac action potential mechanisms.
• Academic Research: A valuable compound for universities and research institutes studying antiarrhythmic agents and their structure-activity relationships.
• Metabolite Studies: Used in the identification and quantification of drug metabolites during pharmacokinetic and pharmacodynamic research.

Basic Information

Product Name	Ajmaline Phenylbarbiturate
CAS No.	81424-61-5
Molecular Formula	C32H38N4O4
Molecular Weight	542.67 g/mol
Synonyms	Ajmaline Phenylbarbiturate; Ajmaline Phenylbarbiturate Salt; 17,21-Secoajmalan-17,21-dione, 1,2,16,17-tetradehydro-19-methyl-, (17R)-, compd. with 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione (1:1); Ajmaline compound with 5-ethyl-5-phenylbarbituric acid; Phenylbarbiturate Ajmaline; Ajmaline Phenobarbital Derivative
EINECS	Contact for details

Quality Control

Our Ajmaline Phenylbarbiturate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and compliance with your research or production protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.