Description

1-(3-Dimethylamino-1-Phenylpropyl)-4-(Cyclopropylmethyl)Piperazine Tri S(Hydrogen Maleate) is a high-purity, non-narcotic pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is essential for research institutions and pharmaceutical manufacturers engaged in the development and production of specialized therapeutic agents.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of novel pharmaceutical compounds, especially non-narcotic analgesics and other CNS-active drugs.
• Research & Development: Serves as a key reagent in medicinal chemistry for the discovery and optimization of new drug candidates in academic and industrial R&D labs.
• API Manufacturing: Used in the commercial-scale production of Active Pharmaceutical Ingredients (APIs) requiring its specific piperazine-based structural motif.
• Chemical Synthesis: Employed in organic synthesis for constructing complex molecular architectures in fine chemical production.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical analysis.

Basic Information

Product Name	1-(3-Dimethylamino-1-Phenylpropyl)-4-(Cyclopropylmethyl)Piperazine Tri S(Hydrogen Maleate)
CAS No.	81402-51-9
Molecular Formula	C25H39N3O12
Molecular Weight	573.60 g/mol
Synonyms	Nefopam Impurity; Nefopam Related Compound; 1-(3-Dimethylamino-1-phenylpropyl)-4-(cyclopropylmethyl)piperazine trimaleate; 4-(Cyclopropylmethyl)-1-[3-(dimethylamino)-1-phenylpropyl]piperazine trimaleate; Nefopam Trimaleate; Acupan Impurity; Fenazoxine Trimaleate; 81402-51-9
EINECS	Contact for details

Quality Control

Our 1-(3-Dimethylamino-1-Phenylpropyl)-4-(Cyclopropylmethyl)Piperazine Tri S(Hydrogen Maleate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.