Description

tert-Butyl (2S)-2-[(tert-Butoxycarbonyl)Amino]-4-Oxobutanoate is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block, enabling the precise construction of complex peptide and small molecule architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics and bioactive compounds.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of peptide-based drugs, protease inhibitors, and other active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce specific amino acid sequences with orthogonal protecting groups.
• Chemical Biology Research: Employed in the study of enzyme mechanisms, protein-protein interactions, and the development of biochemical probes.
• Agrochemical Development: Acts as a precursor in the creation of chiral, biologically active compounds for crop protection agents.
• Academic & Industrial R&D: Serves as a versatile starting material for novel organic transformations and methodology development in synthetic chemistry.

Basic Information

Product Name	tert-Butyl (2S)-2-[(tert-Butoxycarbonyl)Amino]-4-Oxobutanoate
CAS No.	81323-59-3
Molecular Formula	C13H23NO5
Molecular Weight	273.33 g/mol
Synonyms	Boc-Asp(OtBu)-semialdehyde; (S)-2-((tert-Butoxycarbonyl)amino)-4-oxobutanoic acid tert-butyl ester; Boc-L-Aspartic acid 1-tert-butyl 4-semialdehyde; N-Boc-L-Aspartic acid β-tert-butyl aldehyde; Boc-Asp(OBut)-H; Nα-Boc-L-aspartic acid β-tert-butyl aldehyde; tert-Butyl (S)-2-((tert-butoxycarbonyl)amino)-4-oxobutanoate; L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-(1,1-dimethylethyl) 4-aldehyde
EINECS	Contact for details

Quality Control

Our production of tert-Butyl (2S)-2-[(tert-Butoxycarbonyl)Amino]-4-Oxobutanoate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with full traceability are provided for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.