Description

2,4-Difluorophenylacetic Acid is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic incorporation of fluorine atoms, which can dramatically alter the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of anti-inflammatory and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the difluorophenyl moiety enhances bioactivity and environmental stability.
• Liquid Crystal Material Precursor: Serves as a starting material for the synthesis of fluorinated liquid crystals used in display technologies.
• Organic Electronics: Employed in the development of novel organic semiconductors and charge-transport materials.
• Peptide Mimetics & Molecular Probes: The acetic acid functionality allows for coupling to create complex molecules for biochemical research and drug discovery.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical companies offering bespoke synthesis services.

Basic Information

Product Name	2,4-Difluorophenylacetic Acid
CAS No.	81228-09-3
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	(2,4-Difluorophenyl)acetic Acid; 2,4-Difluorobenzeneacetic Acid; α-(2,4-Difluorophenyl)acetic Acid; 2-(2,4-Difluorophenyl)acetic Acid; NSC 405124; 81228-09-3; Difluorophenylacetic Acid
EINECS	Contact for details

Quality Control

Our 2,4-Difluorophenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its acidic nature, handle with appropriate personal protective equipment in a controlled environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.