Description

1-Octyne, 8-Bromo- is a valuable terminal bromoalkyne building block used in advanced organic synthesis. Its bifunctional nature, featuring both a reactive alkyne and a bromine handle, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for applications such as cross-coupling reactions and the synthesis of novel polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides by introducing alkyne-functionalized side chains.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers, dendrimers, and conductive materials.
• Chemical Biology & Bioconjugation: Employed in click chemistry (e.g., CuAAC) for labeling biomolecules, developing probes, and protein modification due to its terminal alkyne group.
• Liquid Crystal & OLED Research: Utilized to synthesize organic semiconductors and liquid crystal compounds with tailored electronic properties.
• Catalyst Ligand Synthesis: A building block for creating sophisticated phosphine or N-heterocyclic carbene (NHC) ligands used in homogeneous catalysis.

Basic Information

Product Name	1-Octyne, 8-Bromo-
CAS No.	81216-13-9
Molecular Formula	C8H13Br
Molecular Weight	189.09 g/mol
Synonyms	8-Bromo-1-octyne; 1-Bromo-7-heptyne; 7-Heptyn-1-yl bromide; Bromoheptyne; Oct-7-yn-1-yl bromide; 7-Octyn-1-yl bromide; Terminal bromoalkyne C8
EINECS	Contact for details

Quality Control

Our 1-Octyne, 8-Bromo- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (HPLC)	≥ 94.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.