Description

Inositol, Myo-, [2-3H(N)] is a tritium-labeled derivative of myo-inositol, a vital cyclic sugar alcohol and secondary messenger precursor. This radiolabeled compound is essential for advanced biochemical and pharmacological research, enabling precise metabolic pathway tracing and receptor binding studies. It is a critical tool for researchers in pharmaceutical development, metabolic disease research, and cell signaling studies who require high-specific-activity tracers for sensitive detection.

Application

• Biochemical Research: As a tracer for studying the metabolism, transport, and cellular uptake of myo-inositol and its phosphorylated derivatives (e.g., IP3).
• Pharmaceutical R&D: For investigating the mechanism of action of drugs targeting inositol signaling pathways, including those for neurological and metabolic disorders.
• Receptor Binding Assays: Used in competitive binding studies to characterize receptors and enzymes involved in the phosphoinositide cycle.
• Metabolic Pathway Analysis: Tracing the incorporation of inositol into phospholipids (phosphatidylinositol) in cell culture and in vivo models.
• Diagnostic Probe Development: Serving as a precursor for developing labeled probes for imaging and diagnostic applications.

Basic Information

Product Name	Inositol, Myo-, [2-3H(N)]
CAS No.	80994-71-4
Molecular Formula	C6H12O6 (tritium labeled)
Molecular Weight	~180.16 g/mol (varies with specific activity)
Synonyms	myo-Inositol (tritiated); 1,2,3,5/4,6-Cyclohexanehexol, tritium-labeled; D-myo-Inositol, [2-3H]; Hexahydroxycyclohexane, [2-3H(N)]; meso-Inositol (tritiated); Vitamin B8 (labeled); Inositol, [2-3H]; Cyclohexane-1,2,3,4,5,6-hexol, [2-3H(N)]
EINECS	Contact for details

Quality Control

Every batch of Inositol, Myo-, [2-3H(N)] is manufactured and analyzed under strict quality systems to ensure radiochemical purity, specific activity, and chemical identity. Quality is verified via analytical techniques including HPLC with radiometric detection and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specific activity (Ci/mmol or GBq/mmol), radiochemical purity, chemical purity, and solvent composition.

Storage

Preserve in the original container as supplied, tightly sealed, and stored at -20°C or below. This product is strictly light-sensitive (protect from all light exposure). For long-term storage, keep frozen. Allow to reach ambient temperature before opening to minimize moisture ingress. Store in accordance with all local and national regulations for radioactive materials.

Specification

Item	Specification
Appearance	Clear colorless to slightly yellow solution
Identification (HPLC/NMR)	Conforms to reference standard
Specific Activity	10-30 Ci/mmol (370-1110 GBq/mmol) (Typical)
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 98%
Concentration	1 mCi/mL (37 MBq/mL) (Typical)
Solvent	Ethanol:Water (9:1) or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.