Description

Methyl 2-[(trifluoromethyl)sulfanyl]acetate is a specialized fluorinated building block featuring a reactive ester group and a trifluoromethylthio (SCF₃) moiety. This compound is valued for its role in introducing the highly lipophilic and metabolically stable SCF₃ group into target molecules, a key modification in modern agrochemical and pharmaceutical design. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for the synthesis of advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for incorporating the SCF₃ pharmacophore into novel active pharmaceutical ingredients (APIs), potentially enhancing membrane permeability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides where the trifluoromethylthio group can improve biological activity and environmental profile.
• Material Science Research: Serves as a precursor for developing fluorinated functional materials, such as specialty polymers or liquid crystals with unique electronic properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and nucleophilic substitutions as an efficient SCF₃ transfer agent or ester component for further derivatization.

Basic Information

Product Name	Methyl 2-[(Trifluoromethyl)Sulfanyl]Acetate
CAS No.	80783-58-0
Molecular Formula	C₄H₅F₃O₂S
Molecular Weight	174.14 g/mol
Synonyms	Methyl (trifluoromethylthio)acetate; Acetic acid, 2-[(trifluoromethyl)thio]-, methyl ester; Methyl 2-(trifluoromethylthio)acetate; 2-[(Trifluoromethyl)thio]acetic acid methyl ester; Methyl trifluoromethylthioacetate; S-Trifluoromethyl thioglycolic acid methyl ester; Methyl ester of 2-(trifluoromethylthio)acetic acid
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-[(trifluoromethyl)sulfanyl]acetate is produced and analyzed under strict quality management protocols. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including GC, HPLC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or an opaque secondary container until use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.