Description

Boc-L-3,4-Dichlorophe CAS NO 80741-39-5 is a protected amino acid derivative, specifically the tert-butoxycarbonyl (Boc) derivative of L-3,4-dichlorophenylalanine. This compound serves as a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, where it introduces the unique 3,4-dichlorophenyl moiety. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for developing novel bioactive compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic peptides and small molecule drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate a modified phenylalanine residue with chlorine substituents.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore the impact of halogenated aromatic side chains on bioactivity.
• API Development: Serves as a building block in the synthetic pathway for potential active pharmaceutical ingredients targeting various diseases.
• Bioconjugation: Can be utilized in the design of peptide-based conjugates for diagnostic or targeted drug delivery applications.
• Chemical Biology Probes: Used to create specialized probes for studying enzyme-substrate interactions or protein function.

Basic Information

Product Name	Boc-L-3,4-Dichlorophe
CAS No.	80741-39-5
Molecular Formula	C₁₄H₁₇Cl₂NO₄
Molecular Weight	334.20 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-3,4-dichloro-L-phenylalanine; Boc-3,4-Dichloro-L-phenylalanine; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-(3,4-dichlorophenyl)propanoic acid; N-Boc-3,4-dichloro-L-phenylalanine; Boc-L-3,4-Dichlorophenylalanine; tert-Butyl (2S)-2-amino-3-(3,4-dichlorophenyl)propanoate; N-tert-Butoxycarbonyl-3,4-dichloro-L-phenylalanine
EINECS	Contact for details

Quality Control

Our Boc-L-3,4-Dichlorophe is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.