Description

2-(2-Amino-4-Fluorophenyl)Acetic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where its unique fluorine-substituted aniline core enables precise molecular modifications. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to incorporate fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides with enhanced activity and selectivity.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe and Dye Chemistry: Employed in the synthesis of fluorophores and molecular probes for diagnostic and imaging applications.
• Peptidomimetics Research: Incorporated into non-natural amino acid analogs and peptide-like structures for biochemical studies.
• Material Science: A monomer or modifier in the production of advanced polymers with specific optical or electronic properties.

Basic Information

Product Name	2-(2-Amino-4-Fluorophenyl)Acetic Acid
CAS No.	80733-63-7
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	2-Amino-4-fluorobenzeneacetic Acid; (2-Amino-4-fluorophenyl)acetic Acid; 4-Fluoro-2-aminophenylacetic Acid; 2-(2-Amino-4-fluorophenyl)ethanoic Acid; 2-Amino-4-fluorophenylacetic Acid; α-(2-Amino-4-fluorophenyl)acetic Acid; 80733-63-7; 2-(2-Amino-4-fluorophenyl)acetic acid
EINECS	Contact for details

Quality Control

Our 2-(2-Amino-4-Fluorophenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.