Description

3-(Bromomethyl)-2-Methyl-1-Naphthonitrile is a versatile brominated naphthonitrile derivative, a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a reactive bromomethyl group and a nitrile functionality, makes it a critical building block for constructing complex heterocyclic and pharmaceutical scaffolds. This high-purity compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly for constructing fused-ring systems common in oncology and CNS therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the naphthalene core provides stability and bioactivity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials due to its rigid aromatic structure.
• Chemical Biology Probes: Utilized to create tagged molecules or photoaffinity labels for studying biological pathways and protein interactions.
• Custom Synthesis and Scale-Up: A fundamental building block for contract research and manufacturing organizations (CROs/CMOs) performing bespoke synthesis for clients.

Basic Information

Item	Detail
Product Name	3-(Bromomethyl)-2-Methyl-1-Naphthonitrile
CAS No.	80665-00-5
Molecular Formula	C₁₃H₁₀BrN
Molecular Weight	260.13 g/mol
Synonyms	2-Methyl-3-(bromomethyl)-1-naphthonitrile; 1-Naphthonitrile, 3-(bromomethyl)-2-methyl-; 3-Bromomethyl-2-methyl-1-naphthonitrile; 2-Methyl-1-cyano-3-bromomethylnaphthalene; 80665-00-5; 3-(Bromomethyl)-2-methylnaphthalene-1-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-(Bromomethyl)-2-Methyl-1-Naphthonitrile is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency meet the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee reliable and reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.