Description

3-Iodobenzyl-Guanidine Hemisulfate is a high-purity chemical intermediate of significant importance in advanced pharmaceutical synthesis and radiopharmaceutical development. This compound matters for its role as a key precursor in the creation of targeted diagnostic and therapeutic agents, particularly in oncology and neurology. It is primarily needed by research institutions, pharmaceutical R&D departments, and manufacturers specializing in the production of innovative radiopharmaceuticals and molecular probes.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of targeted therapeutic agents and diagnostic radiopharmaceuticals.
• Radiopharmaceutical Development: Key building block for compounds used in Positron Emission Tomography (PET) and Single-Photon Emission Computed Tomography (SPECT) imaging.
• Oncology Research: Used in the development of novel cancer theranostics that combine diagnostic and therapeutic functions.
• Neuroendocrine Tumor Targeting: Serves as a structural analog in the development of MIBG (metaiodobenzylguanidine) related compounds for diagnostic and therapeutic applications.
• Bioconjugation Chemistry: Employed in the labeling of peptides, antibodies, and other biomolecules with radioactive iodine isotopes.
• Chemical Biology & Proteomics: Utilized as a molecular probe in research to study enzyme activity, receptor binding, and cellular pathways.
• Reference Standard: Serves as an analytical standard for quality control and method validation in pharmaceutical manufacturing.

Basic Information

Product Name	3-Iodobenzyl-Guanidine Hemisulfate
CAS No.	80663-96-3
Molecular Formula	C8H10IN3 · ½H2SO4
Molecular Weight	Contact for details
Synonyms	3-Iodobenzylguanidine Hemisulfate; 3-Iodo-benzylguanidine Hemisulfate; m-Iodobenzylguanidine Hemisulfate; MIBG Hemisulfate; Guanidine, N-(3-iodophenyl)methyl-, sulfate (1:?); 1-(3-Iodobenzyl)guanidine Hemisulfate; 3-Iodo-benzyl-guanidine Hemisulfate Salt
EINECS	Contact for details

Quality Control

Our 3-Iodobenzyl-Guanidine Hemisulfate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the product should be kept under conditions of low humidity. For long-term stability, storage at 2-8°C is recommended.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.