Description

5-(Aminosulphonyl)-n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2,3-Dimethoxybenzamide is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture. This compound matters for its critical role in the synthesis of specialized active pharmaceutical ingredients (APIs), where its specific functional groups enable precise chemical transformations. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development and production of sophisticated therapeutic agents, particularly within the central nervous system (CNS) and other specialized drug classes.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the research and development of compounds targeting specific neurological pathways and receptors.
• Preclinical & Clinical Development: Serves as a critical material for producing candidate drugs during early-stage and clinical trial manufacturing.
• Process Chemistry: Employed in route scouting and optimization for the efficient, scalable production of target molecules.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Custom Synthesis: A starting point for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.

Basic Information

Product Name	5-(Aminosulphonyl)-n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2,3-Dimethoxybenzamide
CAS No.	80623-13-8
Molecular Formula	C₁₇H₂₇N₃O₅S
Molecular Weight	385.48 g/mol
Synonyms	5-(Aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2,3-dimethoxybenzamide; 2,3-Dimethoxy-5-sulfamoyl-N-[(1-ethylpyrrolidin-2-yl)methyl]benzamide; Benzamide, 5-(aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2,3-dimethoxy-; 80623-13-8; L-741,626; L741626
EINECS	Contact for details

Quality Control

Our 5-(Aminosulphonyl)-n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2,3-Dimethoxybenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.