Description

2-Ethynyl-1,3-Dithiane is a specialized sulfur-containing heterocyclic building block featuring a reactive ethynyl group. This compound matters as a versatile synthon in advanced organic synthesis, enabling the construction of complex molecular architectures through click chemistry and cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting sulfur-containing heterocycles.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the dithiane moiety can impart specific biological activity.
• Polymer & Materials Science: Serves as a functional monomer or cross-linking agent in the development of specialty polymers, resins, and advanced materials with tailored properties.
• Ligand & Catalyst Development: Employed as a precursor for creating novel ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed transformations.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems, leveraging its reactive alkyne handle for bioconjugation.
• Academic & Industrial Research: A valuable reagent for methodological development in organic synthesis, including cycloaddition and annulation reactions.

Basic Information

Product Name	2-Ethynyl-1,3-Dithiane
CAS No.	80593-70-0
Molecular Formula	C6H8S2
Molecular Weight	144.26 g/mol
Synonyms	2-Ethynyl-1,3-dithiane; 1,3-Dithiane, 2-ethynyl-; 2-Ethynyl-1,3-dithiacyclohexane; 2-Ethynyl-m-dithiane
EINECS	Contact for details

Quality Control

Our 2-Ethynyl-1,3-Dithiane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.