Description

Rac 2-Cyano-2-Phenylbutanamide is a versatile chiral building block and synthetic intermediate of significant importance in organic chemistry. Its core value lies in its cyano and amide functional groups, which make it a critical precursor for the synthesis of more complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for asymmetric synthesis and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Used as a building block for creating advanced herbicides, fungicides, and insecticides with specific stereochemical configurations.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where precise molecular architecture is required.
• Academic and R&D Laboratories: A valuable compound for methodological studies in organic synthesis, including new cyanation and amidation reactions.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific optical or mechanical properties.

Basic Information

Product Name	Rac 2-Cyano-2-Phenylbutanamide
CAS No.	80544-75-8
Molecular Formula	C11H12N2O
Molecular Weight	188.23 g/mol
Synonyms	2-Cyano-2-phenylbutyramide; (±)-2-Cyano-2-phenylbutanamide; DL-2-Cyano-2-phenylbutanamide; α-Cyano-α-phenylbutyramide; 2-Phenyl-2-cyanobutyramide; Butanamide, 2-cyano-2-phenyl-; Butyramide, 2-cyano-2-phenyl-
EINECS	Contact for details

Quality Control

Our Rac 2-Cyano-2-Phenylbutanamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Raccemic mixture (50:50)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.