Description

n-(Phthalimidomethyl)Acrylamide is a specialized acrylamide derivative featuring a phthalimide-protected amine group, making it a valuable bifunctional monomer and synthetic intermediate. This compound matters for its ability to introduce polymerizable acrylamide functionality alongside a protected amine that can be selectively deprotected for further chemical modification. Industries that need it include pharmaceutical research for prodrug synthesis, polymer science for creating functionalized resins and hydrogels, and advanced materials development for cross-linked networks and surface coatings.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs and active pharmaceutical ingredients (APIs) where controlled release or targeted delivery is required.
• Functional Polymer Synthesis: Serves as a key monomer for producing specialty polymers, acrylic resins, and hydrogels with reactive pendant groups.
• Cross-linking Agent: Employed in the manufacture of cross-linked polymeric networks for coatings, adhesives, and advanced composite materials.
• Bioconjugation Chemistry: Acts as a linker molecule for attaching biomolecules (e.g., peptides, proteins) to synthetic polymers or surfaces.
• Research & Development: Utilized in academic and industrial R&D for exploring new polymeric architectures and drug delivery systems.
• Photoresist and Electronic Materials: A potential component in the formulation of photosensitive polymers for microelectronics and lithography.

Basic Information

Product Name	n-(Phthalimidomethyl)Acrylamide
CAS No.	80500-44-3
Molecular Formula	C12H10N2O3
Molecular Weight	230.22 g/mol
Synonyms	N-(Phthalimidomethyl)acrylamide; 2-(Acrylamidomethyl)isoindoline-1,3-dione; Acrylamide, N-(phthalimidomethyl)-; N-Acrylamidomethylphthalimide; Phthalimidomethyl acrylamide; N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-ylmethyl)acrylamide; 80500-44-3; NSC 334365
EINECS	Contact for details

Quality Control

Our n-(Phthalimidomethyl)Acrylamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), melting point, and impurity profile is provided with every shipment to guarantee it meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	145 - 150 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.