Description

n-Chloroacetyliodotyramine is a specialized iodinated aromatic compound featuring a chloroacetyl functional group. This chemical serves as a crucial synthetic intermediate in the development of novel bioactive molecules, particularly in pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for applications such as targeted drug discovery and the synthesis of potential radiopharmaceutical agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting thyroid hormone pathways or requiring iodine labeling.
• Radiopharmaceutical Precursor: Used in research for developing iodine-123 or iodine-131 labeled compounds for diagnostic imaging or therapeutic applications.
• Bioconjugation Chemistry: The reactive chloroacetyl group enables conjugation to peptides, proteins, or other biomolecules for creating targeted probes.
• Organic Synthesis Research: Valuable intermediate in academic and industrial laboratories for constructing complex iodinated aromatic structures.
• Biochemical Tool Development: Employed in the creation of enzyme inhibitors or receptor ligands for biochemical and pharmacological studies.

Basic Information

Item	Detail
Product Name	n-Chloroacetyliodotyramine
CAS No.	80465-54-9
Molecular Formula	C10H11ClINO2
Molecular Weight	339.56 g/mol
Synonyms	4-[2-(Chloroacetamido)ethyl]-2-iodophenol; 2-Iodo-4-(2-chloroacetamidoethyl)phenol; N-(2-(4-Hydroxy-3-iodophenyl)ethyl)-2-chloroacetamide; Chloroacetyl iodotyramine; Iodotyramine chloroacetamide derivative
EINECS	Contact for details

Quality Control

Our n-Chloroacetyliodotyramine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and specifications can be aligned with customer-specific requirements for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.