Description

Beta Lipotropin (88-91) CAS NO 80434-83-9 is a synthetic peptide fragment corresponding to residues 88-91 of the β-lipotropin hormone, a key sequence involved in melanocyte-stimulating activity. This compound is of significant interest for research into melanocortin receptor pathways and related physiological processes. It serves as a critical biochemical tool for pharmaceutical R&D, academic research, and diagnostic development, particularly in studies of skin pigmentation, inflammation, and energy homeostasis.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of melanocortin receptors (MC1R, MC3R, MC4R, MC5R).
• Pharmaceutical Development: Serves as a key intermediate or lead compound in the discovery of drugs targeting pigmentation disorders, obesity, and inflammatory conditions.
• Diagnostic Reagents: Employed in the development of immunoassays and test kits to measure related hormones or receptor activity.
• Cell Signaling Studies: Applied in vitro to investigate intracellular signaling cascades activated by melanocortin peptides.
• Neuroscience Research: Utilized in models exploring the role of melanocortins in feeding behavior, energy balance, and neuroprotection.
• Cosmeceutical Research: Investigated for potential applications in topical formulations aimed at modulating skin pigmentation.

Basic Information

Product Name	Beta Lipotropin (88-91)
CAS No.	80434-83-9
Molecular Formula	C24H41N7O6
Molecular Weight	523.63 g/mol
Synonyms	β-Lipotropin (88-91); LPH (88-91); β-LPH (88-91); H-Lys-Asp-Glu-Gly-OH; Lys-Asp-Glu-Gly; K-D-E-G; Melanotropin γ-1; γ1-MSH; Melanocyte-Stimulating Hormone γ-1; γ-MSH (1-4); Acetyl-γ-MSH (1-4) amide (unacetylated, non-amidated fragment)
EINECS	Contact for details

Quality Control

Our Beta Lipotropin (88-91) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis to meet specific purity requirements (e.g., >95%, >98%) is available.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms to theoretical values
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.