Description

(-)-(1S,2R,3R,4S)-3,4-Dihydroxy-1,2-Epoxy-1,2,3,4-Tetrahydrobenz(A)Ant Hracene CAS NO 80433-81-4 is a high-purity, stereochemically defined polycyclic aromatic hydrocarbon (PAH) derivative. This compound is a critical intermediate and reference standard in advanced organic synthesis and toxicological research. It is essential for researchers and manufacturers in the pharmaceutical, environmental science, and chemical synthesis sectors who require precise molecular tools for studying metabolic pathways, mutagenicity, and developing novel chemical entities.

Application

• Biochemical Research: Used as a reference standard and metabolite in studies of polycyclic aromatic hydrocarbon (PAH) activation, DNA adduct formation, and carcinogenicity mechanisms.
• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of complex organic molecules and potential therapeutic agents.
• Toxicology & Safety Assessment: Employed in in vitro and in vivo assays to evaluate the genotoxic and mutagenic potential of related environmental contaminants.
• Analytical Chemistry: Functions as a high-purity calibration standard for chromatographic (HPLC, GC-MS) and spectroscopic analysis in environmental and forensic laboratories.
• Academic Research: Utilized in organic chemistry and medicinal chemistry programs for investigating stereoselective reactions and epoxide chemistry.

Basic Information

Product Name	(-)-(1S,2R,3R,4S)-3,4-Dihydroxy-1,2-Epoxy-1,2,3,4-Tetrahydrobenz(A)Anthracene
CAS No.	80433-81-4
Molecular Formula	C18H14O3
Molecular Weight	278.30 g/mol
Synonyms	(-)-anti-3,4-Dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrobenz[a]anthracene; (-)-anti-BaPDE; anti-Benz[a]anthracene-3,4-diol-1,2-epoxide; 1,2-Epoxy-3,4-dihydroxy-1,2,3,4-tetrahydrobenz[a]anthracene; (-)-anti-BA-3,4-diol-1,2-epoxide; BA-anti-DE; Stereoisomer of Benzanthracene diol epoxide
EINECS	Contact for details

Quality Control

Our (-)-(1S,2R,3R,4S)-3,4-Dihydroxy-1,2-Epoxy-1,2,3,4-Tetrahydrobenz(A)Anthracene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for reference materials, and specifications can be tailored to meet specific research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.