Description

Mafoprazine CAS NO 80428-29-1 is a high-purity chemical compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or active ingredient in the synthesis of novel therapeutic agents, particularly within the central nervous system (CNS) and gastrointestinal domains. It is essential for R&D laboratories and production facilities focused on developing next-generation pharmaceutical products, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of proprietary drug candidates targeting specific receptor pathways.
• Neuropharmacology Research: Used in preclinical studies for investigating compounds with potential psychotropic or neurological activity.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structure for the development of new APIs, especially for gastrointestinal and antiemetic applications.
• Chemical Reference Standard: Provides a certified standard for analytical method development, validation, and quality control testing in pharmaceutical manufacturing.
• Academic & Institutional Research: Utilized in university and institutional labs for medicinal chemistry programs and pharmacological profiling.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for scale-up synthesis and cGMP production runs.

Basic Information

Product Name	Mafoprazine
CAS No.	80428-29-1
Molecular Formula	C19H21FN2O2S
Molecular Weight	360.45 g/mol
Synonyms	Mafoprazine; 1-(2-Fluorophenyl)-4-[(4-methyl-1-piperazinyl)methyl]-5H-pyrido[4,3-b]indol-8-ol; FG-5606; FG5606; 5H-Pyrido[4,3-b]indol-8-ol, 1-(2-fluorophenyl)-4-[(4-methyl-1-piperazinyl)methyl]-
EINECS	Contact for details

Quality Control

Our Mafoprazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC and GC. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support development and commercial projects requiring material that meets cGMP and ICH Q7 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.