Description

3-Fluorobenzylphosphonic Acid CAS NO 80395-16-0 is a high-purity organophosphorus compound featuring a benzylphosphonic acid core substituted with a fluorine atom at the meta position. This specific molecular architecture makes it a versatile and valuable building block in advanced organic synthesis and materials science. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug research.
• Agrochemical Synthesis: Used as a precursor in the manufacture of herbicides, fungicides, and plant growth regulators, leveraging the phosphonic acid moiety for bioactivity.
• Ligand and Catalyst Preparation: Serves as a chelating ligand for metal complexes in homogeneous catalysis and material synthesis.
• Surface Modification Agent: Employed to functionalize metal oxides and other surfaces to alter wettability, adhesion, or corrosion resistance.
• Flame Retardant Additive: Acts as a reactive component in polymers and resins to enhance flame-retardant properties.
• Research & Development: A critical reagent in academic and industrial labs for exploring new reactions in organophosphorus chemistry and medicinal chemistry.

Basic Information

Product Name	3-Fluorobenzylphosphonic Acid
CAS No.	80395-16-0
Molecular Formula	C7H8FO3P
Molecular Weight	190.11 g/mol
Synonyms	(3-Fluorophenyl)methylphosphonic Acid; 3-Fluorobenzylphosphonic Acid; m-Fluorobenzylphosphonic Acid; (3-Fluorobenzyl)phosphonic Acid; Phosphonic acid, P-[(3-fluorophenyl)methyl]-; 80395-16-0; 3-Fluoro-α-(phosphonomethyl)benzenemethanol (tautomer)
EINECS	Contact for details

Quality Control

Our 3-Fluorobenzylphosphonic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and identity confirmation. Our quality commitment supports applications requiring reliable and traceable raw materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.