Description

Properdin is a key regulatory protein of the alternative complement pathway, playing a crucial role in innate immunity by stabilizing the C3 convertase complex. Its high purity and biological activity are essential for reliable research and diagnostic applications in immunology and complement system studies. This product is primarily utilized by researchers in pharmaceutical R&D, biotechnology, and clinical diagnostics, as well as by manufacturers of in-vitro diagnostic (IVD) kits and reagents.

Application

• Biomedical Research: Fundamental studies on the alternative pathway of the complement system, host-pathogen interactions, and inflammatory diseases.
• Drug Discovery & Development: Target validation and screening for therapeutic agents aimed at modulating complement activity in autoimmune and inflammatory disorders.
• Diagnostic Reagent Production: A critical component in the manufacturing of enzyme-linked immunosorbent assay (ELISA) kits and other immunoassays for complement pathway analysis.
• Clinical Research: Investigation of properdin deficiencies and their correlation with susceptibility to infections, such as meningococcal disease.
• Quality Control & Standardization: Serves as a reference standard for the calibration and validation of assays measuring complement function in clinical and research laboratories.

Basic Information

Product Name	Properdin
CAS No.	80295-64-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Complement Factor P; Factor P; P Factor; Properdin Factor P; C3 Nephritic Factor Cofactor; Properdin, Human; Complement Properdin
EINECS	Contact for details

Quality Control

Our Properdin is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and biological activity. Each lot is characterized for purity and functional activity using advanced analytical techniques. A comprehensive Certificate of Analysis (COA), detailing specifications, test methods, and results, is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting and storing at ≤ -20°C under desiccated conditions to maintain optimal stability and activity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Corresponds to standard
Purity (HPLC)	≥ 95%
Protein Content	Determined by UV absorbance
Biological Activity (Functional Assay)	Confirmed
Endotoxin Level	< 1.0 EU/μg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.