Description

Complement C3D CAS NO 80295-45-0 is a high-purity biochemical reagent, specifically a component of the complement system, which is a crucial part of the innate immune response. This product is essential for research and development in immunology, diagnostics, and therapeutic discovery, where precise and reliable components are required to study immune pathways and disease mechanisms. It is primarily needed by biotechnology firms, pharmaceutical R&D laboratories, and diagnostic kit manufacturers focused on autoimmune diseases, inflammatory conditions, and complement-targeted therapies.

Application

• Immunological Research: Used as a critical reagent in studying the classical and alternative complement pathways, their activation, and regulatory mechanisms.
• Diagnostic Assay Development: Serves as a key component in the development of enzyme-linked immunosorbent assays (ELISAs) and other immunoassays for detecting complement activation products.
• Biopharmaceutical Production: Employed in quality control and functional assays during the development of monoclonal antibodies and other biologics that interact with the complement system.
• Therapeutic Target Validation: Used in preclinical studies to validate novel drug targets within the complement cascade for conditions like paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).
• Clinical Laboratory Testing: Incorporated into standardized test kits for clinical laboratories to assess complement function in patient serum samples.
• Academic Research: Supports fundamental research in universities and institutes exploring innate immunity, host-pathogen interactions, and inflammatory disease models.

Basic Information

Product Name	Complement C3D
CAS No.	80295-45-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Complement Component 3d; C3d Fragment; C3d,g; Complement C3dg; C3d,g Fragment; C3 Degradation Product; Third Complement Component, d Fragment; C3d Complement Protein
EINECS	Contact for details

Quality Control

Our Complement C3D is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, functional activity assays, and endotoxin level verification. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. For optimal performance, aliquot the product upon receipt and store under recommended conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (SDS-PAGE)	Complies
Purity (HPLC)	≥ 95%
Protein Content	As per COA
Biological Activity (Functional Assay)	As per COA
Endotoxin Level	< 1.0 EU/mg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.