Description

Complement C1 From Human Serum is a purified, high-purity protein complex that serves as the initiating component of the classical complement pathway. This product is essential for research and development in immunology, providing a critical reagent for studying innate immune responses, autoimmune diseases, and complement system deficiencies. It is primarily utilized by biotechnology firms, pharmaceutical R&D laboratories, and academic research institutions focused on immunology, diagnostics, and therapeutic development.

Application

• Immunological Research: Fundamental studies on the activation and regulation of the classical complement pathway.
• Diagnostic Reagent Manufacturing: Used as a key component in immunoassays and diagnostic kits for detecting complement activity or deficiencies.
• Biopharmaceutical Development: Serves as a critical raw material or reference standard in the development of therapeutics targeting autoimmune and inflammatory disorders.
• Quality Control & Standardization: Acts as a reference material for calibrating assays and ensuring batch-to-batch consistency in related biological products.
• Cell Culture & In Vitro Studies: Used in model systems to investigate the role of complement in disease mechanisms and cell signaling.

Basic Information

Product Name	Complement C1 From Human Serum
CAS No.	80295-32-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Complement C1; Complement Component C1; C1 Complex; C1 Esterase; Human Complement C1; C1qrs Complex; Classical Pathway Complement C1; Serum Complement C1
EINECS	Contact for details

Quality Control

Our Complement C1 From Human Serum is produced and tested under stringent quality management systems to ensure the highest standards of purity and biological activity. Each lot is characterized for functional activity and purity using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications for identity, purity, activity, and safety (endotoxin levels).

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Avoid repeated freeze-thaw cycles to maintain stability and activity.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (Functional Assay)	Conforms
Purity (SDS-PAGE)	≥ 90%
Protein Content (Biuret)	Contact for details
Specific Activity	Contact for details
Endotoxin (LAL)	< 1.0 EU/mg protein
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.