Description

4-(Trifluoromethoxy)Benzoyl Cyanide is a versatile and high-value fluorinated aromatic intermediate. This compound is critical for the synthesis of advanced molecules, particularly in the pharmaceutical and agrochemical sectors, where the trifluoromethoxy group imparts desirable properties like metabolic stability and lipophilicity. It is primarily sought after by research institutions and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethoxy moiety.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Synthesis & Research: A valuable reagent for introducing the 4-(trifluoromethoxy)benzoyl group into complex molecular architectures in medicinal and process chemistry.
• Specialty Polymer Modifier: Can be utilized to synthesize monomers that impart unique chemical resistance and stability to high-performance polymers.

Basic Information

Product Name	4-(Trifluoromethoxy)Benzoyl Cyanide
CAS No.	80277-36-7
Molecular Formula	C9H4F3NO2
Molecular Weight	215.13 g/mol
Synonyms	4-(Trifluoromethoxy)benzoyl cyanide; α-Oxo-4-(trifluoromethoxy)benzeneacetonitrile; 2-[4-(Trifluoromethoxy)phenyl]-2-oxoacetonitrile; 4-(Trifluoromethoxy)benzaldehyde cyanohydrin ketone; p-(Trifluoromethoxy)benzoyl cyanide; 4-(Trifluoromethoxy)benzoyl nitrile
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Benzoyl Cyanide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.